C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 16/24 (2006.01) A61K 9/08 (2006.01) A61K 9/14 (2006.01) A61K 9/50 (2006.01) A61K 39/395 (2006.01) A61P 37/02 (2006.01) C07K 16/00 (2006.01)
Patent
CA 2667655
The present invention relates to a batch crystallization method for crystallizing an anti-hTNFalpha antibody which allows the production of said antibody on an industrial scale; antibody crystals as obtained according to said method; compositions containing said crystals as well as methods of use of said crystals and compositions.
La présente invention concerne un procédé de cristallisation discontinu qui permet de cristalliser un anticorps anti-hTNFalpha, ledit procédé permettant la production dudit anticorps à l'échelle industrielle. L'invention concerne également des cristaux d'anticorps obtenus selon ledit procédé, des compositions contenant lesdits cristaux ainsi que des procédés d'utilisation desdits cristaux et desdites compositions.
Borhani David W.
Fraunhofer Wolfgang
Gottschalk Stefan
Koenigsdorfer Anette
Krause Hans-Juergen
Abbott Biotechnology Ltd.
Torys Llp
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