Crystalline base of...

C - Chemistry – Metallurgy – 07 – D

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C07D 295/073 (2006.01) A61K 31/495 (2006.01) A61P 25/18 (2006.01)

Patent

CA 2597622

Crystalline base of compound trans-1-((1R,3S)-6-chloro-3-phenylindan-1-yl)-3,3- dimethylpiperazine, processes for the preparation of purified free base or salts of this compound, pharmaceutical compositions comprising the base and medical use thereof, including for treatment of schizophrenia and other psychotic disorders.

L~invention concerne une base cristalline de la trans-1-[(1R,3S)-6-chloro-3-phénylindan-1-yl]-3,3-diméthylpipérazine, des procédés permettant de préparer la base libre purifiée ou des sels dudit composé, des compositions pharmaceutiques comprenant la base et leur usage médical, notamment pour traiter la schizophrénie et d~autres troubles psychotiques.

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