Crystalline cephem carboxylic acid addition salt

Details Crystalline cephem carboxylic acid addition salt Crystalline cephem carboxylic acid addition salt

C - Chemistry, Metallurgy

07

D

260/109, 260/104

C07D 501/46 (2006.01) A61K 31/545 (2006.01) C07D 501/00 (2006.01)

Patent

CA 1282407

ABSTRACT OF THE DISCLOSURE A storage stable form of the crystalline sulfate of 7-[2-(2-aminothiazol-4-yl)-(Z)-2-methoxyiminoacetamido]- 3-[5-(2-hydroxyethyl)-4-methylthiazoliomethyl]-3-cephem- 4-carboxylate has a specified X-ray diffraction pattern and is prepared by adding aqueous sulfuric acid to an aqueou6 solution of the compound under controlled conditions.

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