Crystalline cinnamide compounds or salts thereof

Details Crystalline cinnamide compounds or salts thereof Crystalline cinnamide compounds or salts thereof

C - Chemistry, Metallurgy

07

F

C07F 9/6558 (2006.01) C07C 57/145 (2006.01) C07C 57/15 (2006.01) A61K 31/675 (2006.01) A61P 25/28 (2006.01) A61P 43/00 (2006.01)

Patent

CA 2712095

Disclosed are crystals of the compound represented by Formula (1), which has A.beta.-production-reducing effects and is a prodrug of compounds effective in treating neural degenerative diseases of which A.beta. is the cause, for example, diseases such as Alzheimer's disease, Down syndrome, etc., and salts thereof or crystals of salts thereof. These are particularly useful as stock for pharmaceutical products.

L'invention concerne des cristaux du composé représenté par la formule (1), qui a des effets de réduction de la production d'Aß et qui est un promédicament de composés efficaces dans le traitement de maladies neurodégénératives dont l'Aß est la cause, par exemple de maladies telles que la maladie d'Alzheimer, la trisomie 21, etc., et de sels de ceux-ci ou des cristaux de sels de celui-ci. Ceux-ci sont particulièrement utiles comme base pour des produits pharmaceutiques.

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