B - Operations – Transporting – 01 – D
Patent
B - Operations, Transporting
01
D
161/38
B01D 9/00 (2006.01) A61K 9/14 (2006.01) C07B 61/00 (2006.01)
Patent
CA 2147279
This invention has for its object to provide a method of inducing a transition in crystalline state of a crystallizable medicinal substance with great ease and improved efficiency and uniformity on a high production scale. According to the invention, an extruder is used for inducing a transition (.DELTA. ? O) from one crystalline state (.DELTA.) to another crystalline state (O) in a crystallizable medicinal substance.
Izumi Shougo
Nakamichi Kouichi
Oka Masaaki
Nippon Shinyaku Co. Ltd.
Osler Hoskin & Harcourt Llp
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