Crystalline deoxyspergualin and process for its preparation

Details Crystalline deoxyspergualin and process for its preparation Crystalline deoxyspergualin and process for its preparation

C - Chemistry, Metallurgy

07

C

260/543.2, 260/5

C07C 277/06 (2006.01) C07C 279/14 (2006.01)

Patent

CA 2017361

In order to improve the heat stability and handling, and reduce the hydroscopicity of deoxyspergualin hydrochloride, it is put up in crystalline form rather than a lyophilized powder. The crystals are formed by crystallizing a conventionally prepared powder or aqueous syrup of deoxyspergualin by standing in a low humidity atmosphere, possibly in the presence of a water-soluble or water miscible organic solvent.

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