C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 237/26 (2006.01) A61K 31/65 (2006.01) A61P 31/00 (2006.01)
Patent
CA 2746585
The present invention relates to crystalline form C of Tigecycline dihydrochloride and to methods for the preparation of the same. Furthermore the present invention relates to the use of crystalline form C of Tigecycline dihydrochloride as an intermediate for the preparation of an anti-infective medicament. Moreover the present invention relates to pharmaceutical compositions comprising crystalline form C of Tigecycline dihydrochloride in an effective amount and to the use of crystalline form C of Tigecycline dihydrochloride as an anti-infective medicament.
La présente invention porte sur la forme cristalline C du dichlorhydrate de tigécycline et sur des procédés pour sa préparation. En outre la présente invention porte sur l'utilisation de la forme cristalline C du dichlorhydrate de tigécycline comme intermédiaire pour la préparation d'un médicament anti-infectieux. De plus la présente invention porte sur des compositions pharmaceutiques comprenant la forme cristalline C du dichlorhydrate de tigécycline en une quantité efficace et sur l'utilisation de la forme cristalline C du dichlorhydrate de tigécycline comme médicament anti-infectieux.
Decristoforo Martin
Hotter Andreas
Pichler Arthur
Wieser Josef
Goudreau Gage Dubuc
Sandoz Ag
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