Crystalline form iv of linezolid

C - Chemistry – Metallurgy – 07 – D

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C07D 263/20 (2006.01) A61K 31/421 (2006.01)

Patent

CA 2572054

The present invention provides a novel crystalline form of linezolid referred to herein as Form IV as well as methods for the preparation and use of Form IV. The present invention provides pharmaceutical compositions that comprise therapeutically effective amounts of Form IV that can be used to treat patients suffering from gram~positive bacterial infections. Various processes for making crystalline linezolid Form IV are disclosed.

L'invention concerne une nouvelle forme cristalline de linézolide appelé forme IV ainsi que des procédés de préparation et d'utilisation de ladite forme IV. L'invention concerne également des compositions pharmaceutiques comprenant des quantités thérapeutiquement efficaces de forme IV pouvant être utilisées pour traiter des patients souffrant d'infections bactériennes à Gram-positif. L'invention concerne enfin des procédés de production de forme IV de linézolide cristallin.

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