Crystalline form of 5(s)-(2'-hydroxyethoxy)-20(s)-camptothecin

Details Crystalline form of 5(s)-(2'-hydroxyethoxy)-20(s)-camptothecin Crystalline form of 5(s)-(2'-hydroxyethoxy)-20(s)-camptothecin

C - Chemistry, Metallurgy

07

D

C07D 491/22 (2006.01) A61K 31/475 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2653298

A crystalline form of 5(S)-(2'-hydroxyethoxy)-20(S)-camptothecin diastereoisomer of 5(RS)-(2'-hydroxyethoxy)-20(S)-camptothecin is described that is characterized by having an X-ray powder diffraction pattern comprising one or more peak intensities expressed in degrees 2.theta. that are selected from the group consisting of 7.2 ± 0.1, 9.4 ± 0.1, 11.02 ± 0.1, 12.00 ± 0.1, 14.54 ± 0.1, 15.2 ± 0.1, 18.92 ± 0.1, 21.86 ± 0.1, 22.74 ± 0.1 and 26.42 ± 0.1. Methods of making and using the compound are also described.

L'invention concerne une forme cristalline de diastéréoisomère de 5(S)-(2'-hydroxyéthoxy)-20(S)-camptothécine de 5(RS)-(2'-hydroxyéthoxy)-20(S)-camptothécine, caractérisée en ce qu'elle présente un motif de diffraction de rayons X sur poudres qui comprend une ou plusieurs intensités de pic exprimées en degrés 2.theta. qui sont sélectionnées dans le groupe comprenant :7,2 ± 0,1; 9,4 ± 0,1; 11,02 ± 0,1; 12,00 ± 0,1;14,54 ± 0,1; 15,2 ± 0,1; 18.92 ± 0,1; 21,86 ± 0,1; 22,74 ± 0,1 et 26,42 ± 0,1. L'invention concerne également des procédés de fabrication et d'utilisation desdits composés.

Affiliated with

Also associated with

Rating

Crystalline form of 5(s)-(2'-hydroxyethoxy)-20(s)-camptothecin does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Crystalline form of 5(s)-(2'-hydroxyethoxy)-20(s)-camptothecin, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Crystalline form of 5(s)-(2'-hydroxyethoxy)-20(s)-camptothecin will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1685006