Crystalline form of atorvastatin hemi calcium

C - Chemistry – Metallurgy – 07 – D

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Details

C07D 207/34 (2006.01) A61K 31/40 (2006.01) A61P 3/06 (2006.01)

Patent

CA 2560282

The present invention relates to novel crystalline form R of atorvastatin hemi calcium salt and hydrates thereof useful as pharmaceutical agents, to methods for their production and isolation, to pharmaceutical compositions which include novel crystalline form R of atorvastatin hemi calcium salt and hydrates thereof and a pharmaceutically acceptable carrier, and to pharmaceutical methods of treatment.

L'invention concerne une forme cristalline R de sel d'hémi-calium d'atorvastatine et des hydrates de celle-ci utiles comme agents pharmaceutiques, des procédés de production et d'isolation de celle-ci, des compostions pharmaceutiques renfermant la forme cristalline R de sel d'hémi-calcium d'atorvastatine et des hydrates de celle-ci, un excipient acceptable sur le plan pharmaceutique et des méthodes pharmaceutiques de traitement.

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