Crystalline form of benzothiazine dioxide salt

C - Chemistry – Metallurgy – 07 – D

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260/243.21

C07D 417/12 (2006.01) F16L 57/00 (2006.01)

Patent

CA 1209572

NOVEL CRYSTALLINE FORM OF BENZOTHIAZINE DIOXIDE SALT Abstract A novel crystalline form of the monoethanolamine salt of N-(2-pyridyl)-2-methyl-4-hydroxy-2H-1,2-benzo- thiazine-3-carboxamide 1,1-dioxide has been prepared. This novel crystalline form is designated as polymorph I and is useful in therapy as a nonsteroidal anti- arthritic agent. Methods for preparing this polymorph from readily available materials are provided.

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