Crystalline form of omeprazole

Details Crystalline form of omeprazole Crystalline form of omeprazole

C - Chemistry, Metallurgy

07

D

C07D 401/12 (2006.01) A61K 31/4439 (2006.01) A61P 1/04 (2006.01)

Patent

CA 2445251

A novel crystalline form of the substrate known under the chemical name 5- methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfiny]-1H- benzimidazole, and having the generic name omeprazole, hereinafter referred to as omeprozole form C, is disclosed. Further, a process for the preparation of omeprazole form C, a pharmaceutical formulation containing omeprazole form C in admixture with pharmaceutically acceptable excipients and the use of omeprazole form C for treatment of gastrointestinal disorders are disclosed.

Nouvelle forme cristalline du substrat connu sous la désignation chimique de 5-méthoxy-2-[[(4-méthoxy-3,5-diméthyl-2-pyridinyl)méthyl]sulfiny]-1H-benzimidazole, portant le nom générique d'omeprazole et désigné ci-dessous comme omeprozole forme C. L'invention concerne aussi un procédé de préparation d'omeprozole forme C, une préparation pharmaceutique contenant de l'omeprozole forme C, avec ajout d'excipients pharmaceutiquement acceptables, et l'utilisation d'omeprazole forme C pour traiter des troubles gastro-intestinaux.

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