Crystalline forms of...

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C - Chemistry, Metallurgy

07

D

C07D 451/04 (2006.01) A61K 31/46 (2006.01)

Patent

CA 2092510

Crystalline monohydrates of endo-2,3-dihydro-N-(8- methyl-8-azabicyclo[3.2.1]oct-3-yl)-2-oxo -1H-benzimida- zole-1-carboxamide hydrochloride and of endo-3-ethyl- 2,3-dihydro-N-(8-methyl-8-azabicyclo[3.2.1]oct-3-yl)-2- oxo-1H-benzimidazole-1-carboxamide hydrochloride of formula (See formula I) (Compound 2a: R = H] (Compound 2b: R - C2H5) the processes for their preparation and pharmaceutical compositions containing them.

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