Crystalline forms of (6r)-l-erythro-tetrahydrobiopterin...

Details Crystalline forms of (6r)-l-erythro-tetrahydrobiopterin... Crystalline forms of (6r)-l-erythro-tetrahydrobiopterin...

C - Chemistry, Metallurgy

07

D

C07D 475/04 (2006.01) A61K 31/519 (2006.01)

Patent

CA 2545968

Crystal forms of (6R)-L-erythro-tetrahydrobiopterin dihydrochloride, hydrates and solvates and processes for their preparation are provided. These crystal forms are either intermedi~ates for the preparation of stable polymorphic form B or are suitable for solid formulations.

L'invention concerne des formes cristallines de dihydrochlorure de (6R)-L-érythro-tétrahydrobioptérine, des hydrates, des solvates et leurs procédés de préparation. Ces formes cristallines sont des produits intermédiaires destinés à la préparation d'une forme B polymorphe stable ou conviennent pour des préparations solides.

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