C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 487/04 (2006.01) A61K 31/519 (2006.01) A61P 35/04 (2006.01)
Patent
CA 2650916
The present invention relates to crystalline forms of 5-chloro-6-{2,6-difluoro-4-[3- (methylamino)propoxy]phenyl}-N-[(1S)-2,2,2- trifluoro- 1 - methylethyl][l,2,4]triazolo[l,5-a]pyrimidin-7-amine salts; processes for the production thereof; pharmaceutical compositions thereof; and methods for inhibiting tumor growth therewith.
La présente invention concerne les formes cristallines des sels de la 5-chloro-6-{2,6-difluoro-4-[3-(méthylamino)propoxy]phényl}-N-[(1S)-2,2,2-trifluoro-1-méthyléthyl][1,2,4]triazolo[1,5-a]pyrimidin-7-amine; leurs procédés de production; les compositions pharmaceutiques les incluant; et les méthodes d'inhibition de croissance tumorale impliquant lesdites compositions.
Blum David M.
Ku Mannching Sherry
Qi Fang Fang
Wu Yanzhong
Torys Llp
Wyeth Holdings Corporation
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