Crystalline forms of a pharmaceutical compound

Details Crystalline forms of a pharmaceutical compound Crystalline forms of a pharmaceutical compound

C - Chemistry, Metallurgy

07

H

C07H 19/23 (2006.01) A61K 31/7056 (2006.01) A61P 25/16 (2006.01)

Patent

CA 2557371

Described are crystalline forms of the pharmaceutical compound "[9S- (9.alpha.,10.szlig.,12.alpha.)]-5,16-Bis[(ethylthio)methyl]-2,3,9,10,11,12- hexahydro-10-hydroxy-9-methyl-1-oxo-9,12-epoxy-1H-diindolo[1,2,3-fg:3',2',1'- kl]pyrrolo[3,4-i][1,6]benzodiazocine-10-carboxylic acid methyl ester", as well as methods for their use and preparation.

L'invention concerne des formes cristallines du composé pharmaceutique "ester méthylique de l'acide [9S-(9?,10.szlig.,12?)]-5,16-<i>bis</i>[(éthylthio)méthyl]-2,3,9,10,11,12-hexahydro-10-hydroxy-9-méthyl-1-oxo-9,12-époxy-1H-diindolo[1,2,3-fg:3',2',1'-kl]pyrrolo[3,4-i][1,6]benzodiazocine-10-carboxylique", ainsi que des procédés pour leur utilisation et leur préparation.

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