Crystalline forms of carbapenem intermediates

Details Crystalline forms of carbapenem intermediates Crystalline forms of carbapenem intermediates

C - Chemistry, Metallurgy

07

D

C07D 205/08 (2006.01)

Patent

CA 2421116

Crystalline forms of [2R-[2.alpha.(R*),3.beta.(R*)]]-3-(1-hydroxyethyl)- .gamma.-methyl-.beta.,4-dioxo-2-azetidinebutanoic acid(4-nitrophenyl)methyl ester and crystalline form of (.gamma. R,2R,3S)-.alpha.-diazo-3-[(1R)-1- hydroxyethyl]-.gamma.-methyl-.beta.,4-dioxo-2-azetidinebutanoic acid (4- nitrophenyl)methyl ester are disclosed.

L'invention concerne les formes cristallines de l'ester (4-nitrophényl) méthylique [2R-[2.alpha.(R*),3.beta.(R*)]]-3-(1-hydroxyéthyle)-.gamma.-méthyl-.beta.,4-dioxo-2-azétidinebutanoique et la forme cristalline de l'ester (4-nitrophényl) méthylique (.gamma. R,2R,3S)-.alpha.-diazo-3-[(1R)-1-hydroxyéthyle-.gamma.-méthyl-.beta.,4-dioxo-2-azétidinebutanoique.

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