Crystalline forms of fluvastatin sodium

Details Crystalline forms of fluvastatin sodium Crystalline forms of fluvastatin sodium

C - Chemistry, Metallurgy

07

D

C07D 209/24 (2006.01) A61K 31/405 (2006.01) A61P 43/00 (2006.01) C30B 29/54 (2006.01)

Patent

CA 2454072

Novel crystalline forms of Fluvastatin sodium hydrates were found, referred to hereinafter as polymorphic Forms C, D, E and F. Furthermore, the present invention is directed to processes for the preparation of these crystalline forms, a process for the preparation of highly crystalline Fluvastatin sodium Form A, and pharmaceutical compositions comprising the crystalline forms.

L'invention concerne de nouveaux hydroxydes de sodium de fluvastatine, dénommées ci-après formes polymorphes C, D, E et F. En outre, l'invention concerne des procédés de préparation de ces formes cristallines, un procédé de préparation de la forme A de sodium de fluvastatine hautement cristalline, et des compositions pharmaceutiques comprenant lesdites formes cristallines.

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