Crystalline forms of pregabalin

C - Chemistry – Metallurgy – 07 – C

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C07C 229/08 (2006.01) A61K 31/197 (2006.01) A61P 25/22 (2006.01)

Patent

CA 2603129

Crystalline form of Pregabalin characterized by X-ray powder diffraction peaks at about 5.8, 18.4, 19.2, 20.7, and 23.7~ 2.theta. ~ 0.2~ 2.theta., methods for its preparation, its pharmaceutical compositions thereof, and methods for the preparation of crystalline form of Pregabalin characterized by X-ray powder diffraction peaks at about 5.7, 15.4, 17.2, 18.2, and 23.0~ 2.theta. ~ 0.2~ 2.theta., are provided.

L'invention concerne une forme cristalline de prégabaline caractérisée par des pics de diffraction de rayons X sur poudres à environ 5,8, 18,4, 19,2, 20,7 et 23,7° 2? ± 0,2° 2?, des procédés de préparation, des compositions pharmaceutiques, ainsi que des procédés de préparation d'une forme cristalline de prégabaline caractérisée par des pics de diffraction de rayons X sur poudres à environ 5,7, 15,4, 17,2, 18,2 et 23,0° 2? ± 0,2° 2?.

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