Crystalline forms of thiazolidinedione compound and its...

C - Chemistry – Metallurgy – 07 – D

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C07D 417/12 (2006.01) A61K 31/427 (2006.01) A61P 3/10 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2728541

It is an object of the present invention to provide the crystalline form of a thiazolidinedione compound, which is effective as a pharmaceutical ingredient for manufacturing a peroxisome proliferator-activated receptor (PPAR) activator and an anticancer pharmaceutical composition. The present invention relates to a crystalline form of a hydrate of 5-(4-{[6-(4-amino-3,5-dimethylphenoxy)-1-methyl-1-H- benzimidazol-2-yl]methoxy}benzyl)-1,3-thiazolidine-2,4-dione dihydrochloride represented by the following formula (I). [Formula 1]

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