Crystalline forms of tigecycline hydrochloride

Details Crystalline forms of tigecycline hydrochloride Crystalline forms of tigecycline hydrochloride

C - Chemistry, Metallurgy

07

C

C07C 237/26 (2006.01) A61K 31/65 (2006.01) A61P 31/00 (2006.01)

Patent

CA 2704536

The present invention relates to crystalline forms A and B of Tigecycline hydrochloride and to methods for the preparation of the same. Furthermore the present invention relates to the use of crystalline forms A and B of Tigecycline hydrochloride as intermediates for the formulation of an anti-infective medicament. Moreover the present invention relates to pharmaceutical compositions comprising crystalline form A of Tigecycline hydrochloride in an effective amount and to the use of crystalline form A of Tigecycline hydrochloride as anti- infective medicament.

La présente invention concerne des formes cristallines A et B d'hydrochlorure de tigécycline et leurs procédés de préparation. La présente invention concerne également l'utilisation des formes cristallines A et B d'hydrochlorure de tigécycline en tant qu'intermédiaires pour la formulation d'un médicament anti-infectieux. La présente invention concerne en outre des compositions pharmaceutiques qui comprennent la forme cristalline A de l'hydrochlorure de tigécycline en une quantité efficace et l'utilisation de la forme cristalline A de l'hydrochlorure de tigécycline en tant que médicament anti-infectieux..

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