Crystalline fumarate salts of 1-azabicyclo[2.2.2]oct...

Details Crystalline fumarate salts of 1-azabicyclo[2.2.2]oct... Crystalline fumarate salts of 1-azabicyclo[2.2.2]oct...

C - Chemistry, Metallurgy

07

D

C07D 519/00 (2006.01) A61K 31/4545 (2006.01) A61P 25/00 (2006.01)

Patent

CA 2506529

The invention provides fumarate salts of N-[1-azabicyclo[2.2.2]oct-3- yl]furo[2,3-c]pyridine-5-carboxamide, compositions, racemic mixtures, or pure enantiomers thereof, and preparation thereof. The fumarate salts are useful to treat diseases or conditions in which .alpha.7 nAChR is known to be involved. Formula (I).

La présente invention concerne des sels fumarates de N-[1-azabicyclo[2.2.2]oct-3-yl]furo[2,3-c]pyridine-5-carboxamide, des compositions, des mélanges racémiques ou des énantiomères purs desdits sels et la préparation de ces produits. Lesdits sels fumarates sont utiles pour traiter des maladies ou états pathologiques dans lesquels .alpha.7 nAChR est connu pour être impliqué.

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