Crystalline hydrate of oral cephalosporin and its composition

C - Chemistry – Metallurgy – 07 – D

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C07D 501/20 (2006.01) A61K 31/545 (2006.01)

Patent

CA 1283405

A crystalline hydrate of oral cephalosporin and its composition - Abstract of the disclosure - An antibacterial, 7.beta.-[(Z)-2-(2-aminothiazol-4-yl)-4-carboxy- but-2-enoylamino]-3-cephem-4-carboxylic acid is stable in a (di or tri)-hydrate crystal form. A pharmacologically effective amount of this hydrate is filled in a gelatin hard capsule and sealed by a band of gelatin to make a stable composition for clinical use after storage for a long time.

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