Crystalline hydrochloride of new beta-lactam antibiotic and...

Details Crystalline hydrochloride of new beta-lactam antibiotic and... Crystalline hydrochloride of new beta-lactam antibiotic and...

C - Chemistry, Metallurgy

07

D

167/187, 260/271

C07D 463/00 (2006.01) A61K 31/43 (2006.01)

Patent

CA 2034592

The crystalline hydrochloride of the antibiotic 7.beta.-[2'-(R)-2'-phenyl-2'-aminoacetamido]-3-chloro-3-(1- carbadethiacephem)-4-carboxylic acid ("LY163892") is described. The crystalline hydrochloride is an antibiotic in its own right and is a valuable intermediate to the corresponding monohydrate form of LY163892. A process for preparing LY163892 crystalline hydrochloride is also provided.

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