Crystalline isoxazole derivative and medical preparation...

Details Crystalline isoxazole derivative and medical preparation... Crystalline isoxazole derivative and medical preparation...

A - Human Necessities

61

K

A61K 31/5377 (2006.01) A61P 29/00 (2006.01) C07D 261/14 (2006.01)

Patent

CA 2441798

Crystalline 3-[(1S)-1-(2-fluorobiphenyl-4-yl) ethyl]-5-{[amino(morpholin-4-yl)methylene]amino}-isoxazole that exhibits the following angle of diffraction (20) and relative intensity in a powder X-ray diffraction pattern, is very easy to handle and stable in a process of its formulation into a pharmaceutical preparation. (see above table)

L'invention concerne un 3-[(1S)-1-(2-fluorobiphényl-4-yl)éthyl]-5-{[amino(morpholine-4-yl)méthylène]amino}isoxazole cristallin présentant les angles de diffraction (2 theta ) et les intensités relatives suivants dans un diagramme de diffraction des rayons X. Le dérivé d'isoxazole est très facile à manipuler dans une préparation et est stable.

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