Crystalline mesoporous oxide based materials useful for the...

C - Chemistry – Metallurgy – 01 – B

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C01B 37/02 (2006.01)

Patent

CA 2529456

The invention describes a new class of crystalline silica material having two levels or porosity and structural order. At the first level, building units are nanoslabs of uniform size having zeolite framework. At the second structural level, nanoslabs are assembled, e.g. linked through their corners, edges or faces following patterns imposed by interaction with cationic surfactant or triblock copolymer molecules. After evacuation of these molecules, microporosity is obtained inside the nanoslabs, and a precise mesoporosity between the nanoslabs depending on the tiling pattern of the zeolite nanoslabs, as evidenced by X-ray diffraction. These materials are useful for the fixation of biologically active species, such as poorly soluble drugs.

La présente invention concerne une nouvelle classe de matière siliceuse cristalline à deux niveaux de porosité et d'ordre structurel. Au premier niveau, les unités de construction sont des nanolingots de dimensions uniformes à structure zéolite. Au second niveau de structure, les nanolingots sont assemblés, par exemple liés par leurs coins, bords ou facettes selon des logiques d'assemblage qu'imposent les interactions avec les molécules de tensioactifs cationiques ou de copolymères triblocs. Après évacuation de ces molécules, les nanolingots restent intérieurement microporeux, avec une mésoporosité précise entre les nanolingots selon l'angle d'inclinaison des nanolingots de zéolite mise en évidence par la diffraction des rayons X. Ces matières conviennent particulièrement pour fixer des espèces biologiquement actives et notamment des médicaments faiblement solubles.

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