Crystalline micronisate of tiotropium bromide

Details Crystalline micronisate of tiotropium bromide Crystalline micronisate of tiotropium bromide

C - Chemistry, Metallurgy

07

D

C07D 451/10 (2006.01) A61K 31/40 (2006.01) A61P 11/00 (2006.01)

Patent

CA 2479652

The invention relates to a micronized crystalline (1alpha, 2beta, 4beta, 5alpha, 7beta)-7-[(hydroxydi-2-thienylacetyl)oxy]-9,9-dimethyl-3-oxa-9- azoniatricyclo[3.3.1.02,4]nonane bromide, methods for the production thereof, and the use thereof for producing a medicament, particularly for producing a medicament having an anticholinergic effect.

L'invention se rapporte à un micronisat cristallin de bromure de (1alpha, 2bêta, 4bêta, 5alpha, 7bêta)-7-[(hydroxydi-2-thiénylacétyl)oxy]-9,9-diméthyl-3-oxa-9-azoniatricyclo[3.3.1.0?2,4¿]nonane, à son procédé de production, ainsi qu'à son utilisation pour produire un médicament, en particulier pour produire un médicament présentant une action anticholinergique.

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