Crystalline modifications of...

C - Chemistry – Metallurgy – 07 – D

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C07D 295/185 (2006.01)

Patent

CA 2581959

The invention relates to novel crystalline modifications of N-.alpha.-(2,4,6- triisopropylphenylsulfonyl)-3-hydroxyamidino-(L)-phenylalanine-4- ethoxycarbonylpiperazide and/or salts thereof, which can be used as pharmaceutical agents. The invention also relates to said novel crystalline modifications containing pharmaceutical compositions and to pharmaceutical uses.

L'invention se rapporte à de nouvelles modifications cristallines du composé N-.alpha.-(2,4,6-triisopropylphénylsulfonyl)-3-hydroxyamidino-(L)-phénylalanin-4-éthoxycarbonylpipérazide et/ou des sels de ce composé, qui peuvent être utilisées en tant que substances pharmaceutiques. La présente invention concerne en outre des compositions pharmaceutiques qui contiennent lesdites nouvelles modifications cristallines, et des utilisations pharmaceutiques de ces nouvelles modifications cristallines.

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