Crystalline penem, its production and use

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 499/88 (2006.01) A61K 31/44 (2006.01)

Patent

CA 2061245

24205-920 Crystalline Penem, Its Production and Use Abstract of the Disclosure A process for producing crystalline acetoxymethyl ester of (+)-(5R,6S)-6-1[(R)-1-hydroxyethyl]-3-(3- pyridyl)-7-oxo-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2- carboxylic acid by adding a poor solvent to a solution of acetoxymethyl ester of (+)-(5R,6S)-6-[(R)-1- hydroxyethyl]-3-(3-pyridyl)-7-oxo-4-thia-1- azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid in a good solvent is disclosed. The crystalline penem compound is useful for an antibacterial agent.

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