Crystalline polymorphic and amorphous forms of benazepril...

C - Chemistry – Metallurgy – 07 – D

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C07D 223/16 (2006.01) A61K 31/55 (2006.01)

Patent

CA 2492949

The present invention is directed to the polymorphic Form B and the amorphous form of Benazepril hydrochloride. The present invention is also directed to processes for the preparation of Form B and the amorphous form of Benazepril hydrochloride, as well as novel processes for the preparation of Form A. Furthermore, the present invention is directed to pharmaceutical compositions comprising these crystalline forms.

La présente invention concerne la forme B polymorphe et la forme amorphe de l'hydrochlorure de benazeprile. Cette invention concerne aussi des processus de préparation de la forme B et de la forme amorphe de l'hydrochlorure de benazeprile, ainsi que de nouveaux processus de préparation de la forme A. Cette invention concerne enfin des compositions pharmaceutiques comprenant ces formes cristallines.

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