C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 215/14 (2006.01) A61K 31/47 (2006.01)
Patent
CA 2108486
A b s t r a c t (R)-(-)-2-cycloheptyl-N-methylsulfonyl- [4-(2-quinolinyl- methoxy)-phenyl]-acetamide, which is an inhibitor of leukotriene synthesis, is prepared in crystalline form by suspending the active compound in non-crystalline form in inert organic solvents, optionally in the presence of water, and, at elevated temperature, converting it by stirring into the crystalline modification. The crystal- line active compound is suitable, in particular, for preparing medicaments having increased storage stability and temperature resistance.
Grunenberg Alfons
Mertens Hubert
Aktiengesellschaft Bayer
Fetherstonhaugh & Co.
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