C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 239/42 (2006.01) A61K 31/505 (2006.01) A61P 3/06 (2006.01)
Patent
CA 2397450
The inven-tion relates to crystalline salts of the compound (E)-7-[4-(4- fluorophenyl)-6-isopropyl-2-[methyl(methyl--sulfonyl)amino]pyrim-idin-5-yl]- (3R,5S)-3,5-dihydrox-yhept-6-enoic acid of formula (I), as well as processes for their manufacture, pharmaceutical compositions containing them, and their uses.
La présente invention concerne des sels cristallisés du composé d'acide (E)-7-[4-(4-fluorophényl)-6-isopropyl-2-[méthyl(méthylsulfonyl)amino]pyrimidin-5-yl]-(3R,5S)-3,5-dihydroxyhept-6-énoïque de formule (I), ainsi que des procédés de préparation de ces sels cristallisés, des compositions pharmaceutiques contenant lesdits sels cristallisés et l'utilisation de ces derniers.
Okada Tetsuo
Taylor Nigel Philip
Astrazeneca Ab
Fetherstonhaugh & Co.
Shionogi & Co. Ltd.
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