Crystalline tiagabine hydrochloride monohydrate, its...

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 409/14 (2006.01) A61K 31/445 (2006.01)

Patent

CA 2107223

The invention provides crystalline hydrochloride monohydrate R-isomer of N-(4,4-di(3-methylthien-2-yl)-but-3-enyl)nipecotic acid. (See formula I) with the generic name Tiagabine hydrochloride, process for its preparation, compositions containing the same and its therapeutic use as anti-epileptic agent.

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