Crystallisation of levobupivacaine and analogues thereof

C - Chemistry – Metallurgy – 07 – D

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C07D 211/60 (2006.01)

Patent

CA 2200355

Levobupivacaine or an analogue thereof is prepared by reaction with a tartaric acid resolving agent in a solvent, in the presence of water and/or less than 0.5 equivalents of the resolving agent.

On prépare la lévobupivacaïne ou un analogue de celle-ci, au moyen d'une réaction avec un agent de séparation de l'acide tartrique dans un solvant, en présence d'eau et/ou de moins de 0,5 équivalent de l'agent de séparation.

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