Crystallization of antibodies or fragments thereof

Details Crystallization of antibodies or fragments thereof Crystallization of antibodies or fragments thereof

C - Chemistry, Metallurgy

07

K

C07K 16/22 (2006.01) A61K 9/16 (2006.01)

Patent

CA 2574828

The present disclosure concerns methods of crystallization and/or concentration of antibody or antibody fragments. The methods comprise contacting an antibody or antibody fragment with a solution comprising a salt of a divalent cation. Crystals and/or protein gels of antibody or antibody fragments are useful in compositions and formulations.

La présente invention a trait à des procédés de cristallisation et/ou de concentration d'anticorps ou de fragments d'anticorps. Les procédés comprennent la mise en contact d'un anticorps ou fragment d'anticorps avec une solution comportant un sel d'un cation divalent. Des cristaux et/ou des gels à base de protéines d'anticorps ou de fragments d'anticorps sont utiles dans des compositions et des préparations.

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