C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
260/516.8, 260/5
C07C 57/30 (2006.01)
Patent
CA 1212693
ABSTRACT OF THE DISCLOSURE Ibuprofen is crystallized from a .delta.H > 8 liquid such as a C1 to C3-alkanol, e.g., methanol, containing solutions thereof to obtain ibuprofen crystals which are equant (cube, sphere or grain) in shape, which ibuprofen crystals have larger average particle size, higher bulk density, lower bulk volume and improved flow properties compared to previously known bulk ibuprofen crystalline materials.
445027
Amin Sanjay I.
Gordon Roger E.
Macrae & Co.
Upjohn Company (the)
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