Crystallization of iodixanol using milling

C - Chemistry – Metallurgy – 07 – C

Patent

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C07C 231/24 (2006.01) C07C 237/46 (2006.01)

Patent

CA 2710577

This invention relates to the manufacture of iodixanol (1,3-bis(acetamido)- N,N'-bis[3,5- bis(2,3-dihydroxypropylaminocarbonyl)-2,4,6-triiodophenyl]-2-hydroxypropane), more specifically to the purification of iodixanol by crystallization by using wet milling.

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