C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/27 (2006.01) C07K 1/30 (2006.01) C07K 14/53 (2006.01) C07K 14/535 (2006.01) C07K 14/715 (2006.01) C12Q 1/02 (2006.01) G01N 33/566 (2006.01) G01N 33/68 (2006.01)
Patent
CA 2137793
The present invention is directed to methods for crystallizing macrophage colony stimulating factor. The present invention is also directed to methods for designing and producing M-CSF agonists and antagonists using information derived from the crystallographic structure of M-CSF. The invention is also directed to methods for screening M-CSF agonists and antagonists. In addition, the present invention is directed to an isolated, purified, soluble and functional M-CSF receptor.
Bohm Andrew
Fear Anna Lisa
Halenbeck Robert
Jancarik Jarmila
Kim Sung-Hou
Borden Ladner Gervais Llp
Chiron Corporation
Novartis Vaccines And Diagnostics Inc.
The Regents Of The University Of California
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