Crystals including a malic acid salt of n-[2-(diethylamino)...

Details Crystals including a malic acid salt of n-[2-(diethylamino)... Crystals including a malic acid salt of n-[2-(diethylamino)...

C - Chemistry, Metallurgy

07

D

C07D 403/06 (2006.01)

Patent

CA 2455050

The present invention provides crystals, and compositions thereof, wherein the crystals include a malic acid salt of N-[2-(diethylamino)ethyl]-5-[(5-fluoro- 1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3- carboxamide. Methods of preparing such crystals are also disclosed.

La présente invention concerne des cristaux et des compositions correspondantes, ces cristaux comprenant un sel d'acide malique de N-[2-(diéthylamino)éthyl]-5-[(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidène)méthyl]-2,4-diméthyl-1H-pyrrole-3-carboxamide. L'invention concerne en outre des procédés de préparation desdits cristaux.

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