Crystals of hydroxynorephedrine derivative

C - Chemistry – Metallurgy – 07 – C

Patent

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Details

C07C 217/60 (2006.01) A61K 31/216 (2006.01) A61P 13/10 (2006.01)

Patent

CA 2458544

It is intended to provide ethyl (-)-2-[4-[2-[[(1S,2R)-2-hydroxy-2-(4- hydroxyphenyl)-1-methylethyl]amino]ethyl-2,5-dimethylphenoxy]acetate hydrochloride, which has excellent effects of stimulating .beta.3 adrenaline receptor and treating urinary frequency and urinary incontinence and a high storage stability and is practically usable as drugs, crystals thereof and medicinal compositions containing the same.

L'invention concerne un chlorhydrate d'éthyl (-)-2-[4-[2-[ [ (1S,2R)-hydroxy-2-(4-hydroxyphényl)-1-méthyléthyl]amino]éthyl-2,5-diméthylphenoxy]acétate qui possède d'excellents effets sur la stimulation du récepteur d'adrénaline .beta.3 et sur le traitement de la fréquence urinaire et de l'incontinence urinaire, ainsi qu'une stabilité élevée lors du stockage. On peut utiliser ce composé comme un médicament. Ladite invention a également trait à des cristaux correspondants et à des compositions médicinales renfermant ledit composé.

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