C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 489/08 (2006.01) A61K 31/485 (2006.01) A61P 13/02 (2006.01) A61P 17/04 (2006.01) A61P 25/04 (2006.01)
Patent
CA 2602968
17-Cyclopropylmethyl-3,14.beta.-dihydroxy-4,5.alpha.-epoxy-6.beta.-[N~methyl- trans-3-(3-furyl)acrylamido]morphinan hydrochloride. It has a high purity and retains constant quality after production. The 17-cyclopropylmethyl-3,14.beta.- dihydroxy-4,5.alpha.-epoxy-6.beta.-[N~methyl-trans-3-(3- furyl)acrylamido]morphinan hydrochloride is in the form of crystals, especially A-form, B-form, and C-form crystals.
L'invention concerne du chlorhydratede 17-cyclopropylméthyl-3,14.beta.-dihydroxy-4,5.alpha.-époxy-6.beta.-[N-méthyl-trans-3-(3-furyl)acrylamido]morphinane. Ce composé présente une grande pureté et conserve une qualité constante après fabrication. Le chlorhydrate de 17-cyclopropylméthyl-3,14.beta.-dihydroxy-4,5.alpha.-époxy-6.beta.-[N-méthyl-trans-3-(3-furyl)acrylamido]morphinane se présente sous forme de cristaux, et en particulier de cristaux de forme A, de forme B et de forme C.
Akimoto Masahiro
Takeda Takahiro
Wakita Hisanori
Smart & Biggar
Toray Industries Inc.
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