C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 401/12 (2006.01) C07D 211/70 (2006.01)
Patent
CA 2188507
Monohydrate and trihydrate crystals of N-(2-(4-(5H-dibenzo[a,d]cyclohepten-5-ylidene)piperidino)ethyl)-1-formyl-4- piperidinecarboxamide hydrochloride having formula (I): (see formula (I)) exhibit excellent stability. The monohydrate crystals exhibit excellent oral absorption, and the trihydrate crystals exhibit a high dissolution rate.
Asai Koji
Fujii Akiko
Kubo Mie
Mihara Ryuichi
Naora Hirokazu
Ajinomoto Co. Inc.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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