Csnk1gs as modifiers of the p21 pathway and methods of use

Details Csnk1gs as modifiers of the p21 pathway and methods of use Csnk1gs as modifiers of the p21 pathway and methods of use

C - Chemistry, Metallurgy

12

Q

C12Q 1/00 (2006.01) A61K 49/00 (2006.01) C07K 14/47 (2006.01) C12Q 1/68 (2006.01) G01N 33/00 (2006.01) G01N 33/53 (2006.01) G01N 33/574 (2006.01)

Patent

CA 2494236

Human CSNK1G genes are identified as modulators of the p21 pathway, and thus are therapeutic targets for disorders associated with defective p21 function. Methods for identifying modulators of p21, comprising screening for agents that modulate the activity of CSNK1G are provided.

L'invention concerne des gènes humains CSNK1G identifiés en tant que modulateurs de la voie p21. Lesdits gènes sont ainsi des cibles thérapeutiques pour des troubles associés à un dysfonctionnement de la p21. L'invention concerne également des procédés pour identifier des modulateurs de la p21, comprenant le criblage d'agents qui modulent l'activité des gènes CSNK1G.

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