Csnks as modifiers of the rac pathway and methods of use

C - Chemistry – Metallurgy – 12 – Q

Patent

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C12Q 1/48 (2006.01) C12N 9/12 (2006.01) C12Q 1/00 (2006.01) C12Q 1/02 (2006.01) G01N 33/53 (2006.01)

Patent

CA 2506634

Human CSNK genes are identified as modulators of the RAC pathway, and thus are therapeutic targets for disorders associated with defective RAC function. Methods for identifying modulators of RAC, comprising screening for agents that modulate the activity of CSNK are provided.

Des gènes MRAC humains sont identifiés comme modulateurs de la voie RB et sont, en conséquence, des cibles thérapeutiques pour des troubles associés à une fonction RAC défectueuse. L'invention concerne des procédés d'identification de modulateurs de RAC, comprenant la sélection d'agents modulant l'activité de MRAC.

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