Cspcna isoform modifications and uses thereof

Details Cspcna isoform modifications and uses thereof Cspcna isoform modifications and uses thereof

C - Chemistry, Metallurgy

07

K

C07K 14/47 (2006.01) G01N 33/50 (2006.01) G01N 33/574 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2612695

Methods and compositions to detect the presence of csPCNA isoform by identifying one or more posttranslational modifications are disclosed. Methods to identify csPCNA isoform through posttranslational modifications including methylesterification levels are disclosed.

L'invention concerne des procédés et des compositions servant à détecter la présence de l'isoforme csPCNA (antigène nucléaire de prolifération cellulaire spécifique au cancer) par identification d'une ou de plusieurs modifications post-translationnelles. L'invention concerne des procédés servant à identifier l'isoforme csPCNA au moyen de modifications post-translationnelles comprenant des niveaux de méthylestérification.

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