Ctaa 28a32, the antigen recognized by mca 28a32

C - Chemistry – Metallurgy – 12 – P

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C12P 21/08 (2006.01) A61K 39/00 (2006.01) A61K 39/395 (2006.01) A61K 47/48 (2006.01) C07K 14/705 (2006.01) C07K 16/30 (2006.01) C07K 16/42 (2006.01) G01N 33/574 (2006.01) G01N 33/577 (2006.01)

Patent

CA 2079601

2079601 9116629 PCTABS00008 The present invention comprises the epitope recognized by the human monoclonal antibody 28A32, the human tumor antigen containing this epitope, which we have identified, isolated and characterized, and human MCA 28A32. The invention also relates to the use of antibodies to the antigen containing this epitope for diagnosis and monitoring of treatment of cancer and to the use of this antigen in the preparation of vaccines to elicit an immune response similar to that obtained against tumor cells containing this epitope.

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