Ctla-4 antibody dosage escalation regimens

A - Human Necessities – 61 – K

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A61K 39/395 (2006.01)

Patent

CA 2630157

A disease or condition, such as cancer or an infectious disease, can be treated in a patient by administering a CTLA-4 antibody in an escalating dosage regimen until a partial or complete response is elicited in the patient or a pre¬ determined maximum dosage is reached.

Selon la présente invention, une maladie ou un état pathologique, tel que le cancer ou une maladie infectieuse, peut être traité chez un patient par administration d'un anticorps CTLA-4 dans un régime d'escalade de dose jusqu'à ce qu'une réponse partielle ou complète soit provoquée chez le patient ou qu'une dose maximale prédéterminée soit atteinte.

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