Cubic liquid crystalline compositions and methods for their...

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A61K 9/127 (2006.01) A61K 9/06 (2006.01) A61K 9/16 (2006.01)

Patent

CA 2434647

A dry powder cubic gel precursor comprising an encapsulating compound, an amphiphile capable of forming a cubic liquid crystalline phase, and optionally a solvent. The encapsulating compound (A), amphiphile (B), and optional solvent (C) are present in mass fractions relative to each other such that 1.0 = a + b + c wherein a is the mass fraction of A, b is the mass fraction of B, and c is the mass fraction of C. Further, 1.0 > a > 0, 1.0 > b > 0, 1.0 > c > 0 and a, b, and c do not fall within a cubic liquid crystalline phase region on a phase diagram representing phase behavior of A, B, and C.

La présente invention concerne, d'une part une poudre sèche précurseur de gel cubique comprenant un composé d'encapsulage, d'autre part un amphiphile capable de former une phase de cristal liquide cubique, et éventuellement un solvant. Le composé d'encapsulage (A), l'amphiphile (B), et le solvant éventuel (C) sont présents dans des rapports massiques tels que 1,0 = a + b + c auquel cas "a" est la fraction massique de A, "b" celle de B, et "c" celle de C. On a en outre 1 > a > 0, 1 > b > 0, 1 > c > 0, "a", "b" et "c" ne se situant pas dans la zone des phases de cristaux liquides cubiques sur le diagramme des phases représentant le comportement en phases de A, B, et C.

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