Cubilin protein, dna sequences encoding cubilin and uses...

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/00 (2006.01) C07K 14/435 (2006.01) C07K 14/705 (2006.01) C12N 15/12 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2319210

The present invention provides novel renal receptors for ligands. Cubilin and megalin are representative examples of such renal receptors. Also provided are potential uses of these renal receptors for treating toxicity in various tissues and for detecting renal damage.

L'invention concerne de nouveaux récepteurs rénaux pour ligands. La cubiline et la mégaline sont des exemples représentatifs de récepteurs rénaux pour ligands. L'invention concerne également des possibilités d'utilisation relatives auxdits récepteurs, pour traiter la toxicité dans différents tissus et pour déceler des dégâts occasionnés sur le plan rénal.

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