C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 5/00 (2006.01)
Patent
CA 2693420
The present invention relates to a culture including a growth medium and a combination of cytokines consisting of i) interleukin-6 (IL6); ii) flt3-ligand (FLT3); iii) stem cell factor (SCF) and iv) thrombopoi- etin (TPO); the use of the culture for expanding.ex vivo stem cells and/or parental cells and cells differentiated therefrom, and the use of said cells obtainable from said expansion.
L'invention concerne une culture contenant un milieu de croissance et une combinaison de cytokines constituée i) d'interleukine-6 (IL6) ; ii) de ligand Flt3 (FLT3) ; iii) de facteur des cellules souches (FCS) ; et iv) de thrombopoïétine (TPO). L'invention concerne également l'utilisation de cette culture dans l'expansion ex vivo de cellules souches et/ou de cellules parentales et de cellules différenciées à partir de celles-ci, ainsi que l'utilisation des cellules obtenues à partir de cette expansion.
Giordano Rosaria
Lazzari Lorenza
Montemurro Tiziana
Rebulla Paolo
Sirchia Girolamo
Fondazione Irccs Ca' Granda - Ospedale Maggiore Policlinico
Mbm Intellectual Property Law Llp
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